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Review
. 2011 Jun;82(4):513-23.
doi: 10.1016/j.fitote.2011.01.018. Epub 2011 Jan 28.

Antioxidant and prooxidant properties of flavonoids

D Procházková  1 , I Boušová, N Wilhelmová
Affiliations
Review

Antioxidant and prooxidant properties of flavonoids

D Procházková et al. Fitoterapia. 2011 Jun.

Abstract

The interest in possible health benefits of flavonoids has increased owing to their potent antioxidant and free radical scavenging activities observed in vitro. Nevertheless, the antioxidant efficacy of flavonoids in vivo is less documented and their prooxidant properties have been actually described in vivo. Due to their prooxidant properties, they are able to cause oxidative damage by reacting with various biomolecules, such as lipids, proteins and DNA. Hence, the aim of this review is to discuss both the antioxidant and prooxidant effects of flavonoids.

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