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. 2010 Dec 30;21(4):273-5.
doi: 10.3802/jgo.2010.21.4.273. Epub 2010 Dec 31.

Sarcoma botryoides (embryonal rhabdomyosarcoma) of the uterine cervix in sisters

Azamsadat Mousavi  1 , Setare Akhavan
Affiliations

Sarcoma botryoides (embryonal rhabdomyosarcoma) of the uterine cervix in sisters

Azamsadat Mousavi et al. J Gynecol Oncol. .

Abstract

Sarcoma botryoides (embryonal rhabdomyosarcoma) rarely arises in the uterine cervix. We report a case of a 14-year-old female with sarcoma botryoides who presented with prolonged vaginal bleeding and cervical polyp. The biopsy specimen confirmed sarcoma botryoides. The patient underwent radical surgery of the tumor and hysterectomy without adjuvant chemotherapy. The sister of the patient had died previously due to the same diagnosis at the age of 17. We achieved a satisfactory outcome in short-term period with radical surgery and hysterectomy. Presence of sarcoma botryoides of the cervix in two sisters in the family highlights the possible role of genetic factors in the development of sarcoma botryoides.

Keywords: Cervical cancer; Rhabdomyosarcoma; Sarcoma botryoides.

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Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

Figures

Fig. 1
Fig. 1
The tumor composed of pleomorphic spindle cells with dark pyknotic nuclei and a few round to oval cells with round nuclei and scant cytoplasm in abundant losse vascular myxoid stroma. The tumor cells detached from each other and forms stromal elements.
Fig. 2
Fig. 2
The tumor composed of pleomorphic elongated spindle cells with some conspicious nucleoli with eosinophilic fibrillar cytoplasm. The spindle cells separated from each other by collagen fibers, with an irregular fascicular growth pattern.
See this image and copyright information in PMC

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