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. 2011 Jan 11:3:RRN1208.
doi: 10.1371/currents.RRN1208.

Genetic risk profiling for prediction of type 2 diabetes

Raluca Mihaescu  1 , James Meigs, Eric Sijbrands, A Cecile Janssens
Affiliations

Genetic risk profiling for prediction of type 2 diabetes

Raluca Mihaescu et al. PLoS Curr. .

Abstract

Type 2 diabetes (T2D) is a common disease caused by a complex interplay between many genetic and environmental factors. Candidate gene studies and recent collaborative genome-wide association efforts revealed at least 38 common single nucleotide polymorphisms (SNPs) associated with increased risk of T2D. Genetic testing of multiple SNPs is considered a potentially useful tool for early detection of individuals at high diabetes risk leading to improved targeting of preventive interventions.

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