Spinal methylene blue is hazardous

Affiliations

¹ Division of Pain Medicine, Department of Anesthesiology, Keck School of Medicine, University of Southern California, 1520 San Pablo St., Suite 3450 Los Angeles, CA 90033, USA. Tel.: +1 323 692 3611.

Comment

Reed Levine et al. Pain. 2011 Apr.

. 2011 Apr;152(4):952-953.

doi: 10.1016/j.pain.2011.01.009. Epub 2011 Feb 1.

¹ Division of Pain Medicine, Department of Anesthesiology, Keck School of Medicine, University of Southern California, 1520 San Pablo St., Suite 3450 Los Angeles, CA 90033, USA. Tel.: +1 323 692 3611.

No abstract available

Comment on

A randomized placebo-controlled trial of intradiscal methylene blue injection for the treatment of chronic discogenic low back pain.
Peng B, Pang X, Wu Y, Zhao C, Song X. Peng B, et al. Pain. 2010 Apr;149(1):124-129. doi: 10.1016/j.pain.2010.01.021. Epub 2010 Feb 18. Pain. 2010. PMID: 20167430 Clinical Trial.

1. Gerrard S. Methylene blue is dangerous (Letter to the Editor). Br Med J. 1980;281:1426-1427.
1. Gross SW. Letter: neurological deficits resulting from intrathecal administration of methylene blue. Neuroradiology. 1974;7:117.
1. Peng B, Pang X, Wu Y, Zhan C, Song X. A randomized placebo-controlled trial of intradiscal methylene blue injection for the treatment of chronic discogenic low back pain. Pain. 2010;149:124-129.
1. Peng B, Zhang Y, Hou S, Wu W, Fu X. Intradiscal methylene blue injection for the treatment of chronic discogenic low back pain. Eur Spine J. 2007;16:33-38.
1. Poppers PJ, Mastri AR, Lebeaux M, Covino BG. The effect of methylene blue on neural tissue. Anesthesiology. 1970;33:335-340.