Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011 Mar 1;21(5):1425-8.
doi: 10.1016/j.bmcl.2011.01.022. Epub 2011 Jan 11.

Pyrrolo[1,2-f]triazines as JAK2 inhibitors: achieving potency and selectivity for JAK2 over JAK3

Lalgudi S Harikrishnan  1 , Muthoni G Kamau, Honghe Wan, Jennifer A Inghrim, Kurt Zimmermann, Xiaopeng Sang, Harold A Mastalerz, Walter L Johnson, Guifen Zhang, Louis J Lombardo, Michael A Poss, George L Trainor, John S Tokarski, Matthew V Lorenzi, Dan You, Marco M Gottardis, Kathy F Baldwin, Jonathan Lippy, David S Nirschl, Ruhui Qiu, Arthur V Miller, Javed Khan, John S Sack, Ashok V Purandare
Affiliations

Pyrrolo[1,2-f]triazines as JAK2 inhibitors: achieving potency and selectivity for JAK2 over JAK3

Lalgudi S Harikrishnan et al. Bioorg Med Chem Lett. .

Abstract

SAR studies of pyrrolo[1,2-f]triazines as JAK2 inhibitors is presented. Achieving JAK2 inhibition selectively over JAK3 is discussed.

PubMed Disclaimer

MeSH terms

LinkOut - more resources