Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2011 Mar;12(3):224.
doi: 10.1038/nrg2867-c1. Epub 2011 Feb 1.

Tests of association for rare variants: case control mutation screening

Comment

Tests of association for rare variants: case control mutation screening

Sean V Tavtigian et al. Nat Rev Genet. 2011 Mar.
No abstract available

PubMed Disclaimer

Comment on

References

    1. Bansal V, Libiger O, Torkamani A, Schork NJ. Statistical analysis strategies for association studies involving rare variants. Nat Rev Genet. 2010;11:773–785. - PMC - PubMed
    1. Asimit J, Zeggini E. Rare Variant Association Analysis Methods for Complex Traits. Annual Review of Genetics. 2010;44:293–308. - PubMed
    1. Terwilliger JD, Ott J. Handbook of Human Genetic Linkage. Johns Hopkins University Press; Baltimore and London: 1994. p. 235.
    1. Tavtigian SV, Byrnes GB, Goldgar DE, Thomas A. Classification of rare missense substitutions, using risk surfaces, with genetic- and molecular-epidemiology applications. Hum Mutat. 2008;29:1342–1354. - PMC - PubMed
    1. FitzGerald MG, et al. Heterozygous ATM mutations do not contribute to early onset of breast cancer. Nat Genet. 1997;15:307–310. - PubMed