Autonomic MC sets the metabolic tone
- PMID: 21284978
- DOI: 10.1016/j.cmet.2011.01.014
Autonomic MC sets the metabolic tone
Abstract
The CNS melanocortin (MC) and the autonomic nervous (ANS) system represent key regulators of energy homeostasis. In this issue, Rossi et al. (2011) dissect metabolic functions of MC4 receptors based on anatomic localization within the ANS by re-expressing MC4R subpopulations in cholinergic or brainstem neurons of MC4R-KO mice.
Copyright © 2011 Elsevier Inc. All rights reserved.
Comment on
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Melanocortin-4 receptors expressed by cholinergic neurons regulate energy balance and glucose homeostasis.Cell Metab. 2011 Feb 2;13(2):195-204. doi: 10.1016/j.cmet.2011.01.010. Cell Metab. 2011. PMID: 21284986 Free PMC article.
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