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Comment
. 2011 Feb 2;13(2):123-4.
doi: 10.1016/j.cmet.2011.01.012.

Adiponectin receptor signaling: a new layer to the current model

Takashi Kadowaki  1 , Toshimasa Yamauchi
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Adiponectin receptor signaling: a new layer to the current model

Takashi Kadowaki et al. Cell Metab. .
Free article

Abstract

Adiponectin and its receptors, AdipoR1 and AdipoR2, regulate glucose and fatty acid metabolism partly via activation of AMP-activated protein kinase (AMPK). Recent work in Nature Medicine (Holland et al., 2011) suggests that adiponectin stimulates ceramidase activity through AdipoR1 and AdipoR2, an activity potentially involved in promoting cell survival.

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