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Case Reports
. 2010 Nov;51(11):1279-82.

Cyclosporine treatment of perianal gland adenoma concurrent with benign prostatic hyperplasia in a dog

Chul Park  1 , Jong-Hyun Yoo, Ha-Jung Kim, Chae-Young Lim, Ju-Won Kim, So-Young Lee, Jung-Hyun Kim, Jae-Im Jang, Hee-Myung Park
Affiliations
Case Reports

Cyclosporine treatment of perianal gland adenoma concurrent with benign prostatic hyperplasia in a dog

Chul Park et al. Can Vet J. 2010 Nov.

Abstract
in English, French

A 13-year-old, intact male, mixed-breed dog was evaluated for multiple intradermal nodules around the anus. The nodules were diagnosed as perianal gland adenoma based on histopathologic examination. After therapy with cyclosporin A for 5 wk, the perianal masses were moderately shrunken. The dog's condition has remained stable over 6 mo.

Traitement à la cyclosporine d’un adénome des glandes péri-anales concomitantes avec une hyperplasie prostatique bénigne chez un chien. Un chien mâle intact de race croisée âgé de 13 ans a été évalué pour des nodules intradermiques multiples autour de l’anus. Les nodules ont été diagnostiqués comme un adénome des glandes péri-anales en se basant sur un examen histopathologique. Après une thérapie à la cyclosporin A pendant 5 semaines, les masses péri-anales étaient modérément réduites. L’état du chien est demeuré stable pendant 6 mois.

(Traduit par Isabelle Vallières)

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Figures

Figure 1
Figure 1
A — These lesions were ulcerated and the rectal mucous membrane was mildly protruded (arrowhead) due to the masses (arrows). B — Two weeks after cyclosporine therapy. Shrinkage of the lesion and mild exudation are apparent (arrowhead). C — Moderate remission of the perianal lesion 5 wk after cyclosporine therapy. Exudation and protrusion of the rectal mucous membrane have disappeared.
Figure 2
Figure 2
A — Lateral abdominal radiograph of the dog showing prostatomegaly. B — Retrograde urethrocystography reveals reflux of contrast media into the prostate gland.
Figure 3
Figure 3
Histopathologically, perianal gland adenoma was clearly observed. In addition, the well-developed stroma surrounding the lobules and hepatoid cells was noted (×100, hematoxylin & eosin).
See this image and copyright information in PMC

References

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