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Comparative Study
. 1990 Oct;8(8):505-7.

[Comparative study of 2 rapid techniques (DNA hybridization and chromatography) for the identification of Mycobacterium tuberculosis complex isolated from clinical specimens]

[Article in Spanish]
J M Artero  1 , E A Herrera, P L Valero, F Martín Luengo
Affiliations
  • PMID: 2128873
Comparative Study

[Comparative study of 2 rapid techniques (DNA hybridization and chromatography) for the identification of Mycobacterium tuberculosis complex isolated from clinical specimens]

[Article in Spanish]
J M Artero et al. Enferm Infecc Microbiol Clin. 1990 Oct.

Abstract

We have compared the capacity of two combined chromatographic methods (gas chromatography and thin-layer chromatography) and a nucleic acid hybridization probe (Gen-Probe) to identify members of the Mycobacterium tuberculosis complex. The results of a single test show 6% of false-negatives with Gen-Probe and 8.5% doubtfuls with chromatography. After repeated, the specificity of both methods was improved to 100%. The advantages and disadvantages of the two methods in relation to its capacity to provide a rapid identification of Mycobacterium tuberculosis are discussed.

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