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Review

One Hundred Years of Discovery and Rediscovery of Helicobacter pylori and Its Association with Peptic Ulcer Disease

Barry J. Marshall  1
Harry LT Mobley  1 , George L Mendz  2 , Stuart L Hazell  3
, editors.
In: Helicobacter pylori: Physiology and Genetics. Washington (DC): ASM Press; 2001. Chapter 3.
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Review

One Hundred Years of Discovery and Rediscovery of Helicobacter pylori and Its Association with Peptic Ulcer Disease

Barry J. Marshall.
Free Books & Documents

Excerpt

Today's understanding of Helicobacter-related gastric diseases in humans stems from an explosion in research, which occurred after the first culture of the organism by Marshall and Warren in 1982 (47). This event may have been the culmination of over 100 years of study of helicobacters and their epiphenomena. This chapter is a concise overview of major highlights during that time following four storylines of spiral bacteria, epidemic gastritis with hypochlorhydria, urease, and bismuth therapy.

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