Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011 Feb;17(2):317-9.
doi: 10.3201/eid1702.100355.

Surface layer protein A variant of Clostridium difficile PCR-ribotype 027

Patrizia Spigaglia, Fabrizio Barbanti, Paola Mastrantonio

Surface layer protein A variant of Clostridium difficile PCR-ribotype 027

Patrizia Spigaglia et al. Emerg Infect Dis. 2011 Feb.
No abstract available

PubMed Disclaimer

Figures

Figure
Figure
Phylogenetic tree based on the alignment of the surface layer protein A amino acid sequence of Clostridium difficile 027 (GenBank accession no. CBE06198) with those of PCR-ribotypes 001, 002, 005, 010, 012, 014, 017, 031, 046, 054, 066, 078, 092, and 094 (GenBank accession nos. AAZ05957, AAZ05964, AAZ05968, AAZ05974, AAZ05975, AAZ05984, AAZ05988, AAZ05989, AAZ05980, AAZ05972, AAZ05986, AAZ05994, AAZ05982, and AAZ05991, respectively). The phylogram was generated by using TreeView version 1.6.6 (http://en.bio-soft.net/tree/TreeView.html). The branch lengths are scaled in proportion to the extent of the change per position, as indicated by the scale bar.
See this image and copyright information in PMC

References

    1. O’Connor JR, Johnson S, Gerding DN. Clostridium difficile infection caused by the epidemic BI/NAP1/027 strain. Gastroenterology. 2009;136:1913–24. 10.1053/j.gastro.2009.02.073 - DOI - PubMed
    1. Calabi E, Calabi F, Phillips AD, Fairweather NF. Binding of Clostridium difficile surface layer proteins to gastrointestinal tissues. Infect Immun. 2002;70:5770–8. 10.1128/IAI.70.10.5770-5778.2002 - DOI - PMC - PubMed
    1. Sára M, Sleytr UB. S-layer proteins. J Bacteriol. 2000;182:859–68. 10.1128/JB.182.4.859-868.2000 - DOI - PMC - PubMed
    1. Pantosti A, Cerquetti M, Viti F, Ortisi G, Mastrantonio P. Immunoblot analysis of serum immunoglobulin G response to surface proteins of Clostridium difficile in patients with antibiotic-associated diarrhea. J Clin Microbiol. 1989;27:2594–7. - PMC - PubMed
    1. Ausiello CM, Cerquetti M, Fedele G, Spensieri F, Palazzo R, Nasso M, et al. Surface layer proteins from Clostridium difficile induce inflammatory and regulatory cytokines in human monocytes and dendritic cells. Microbes Infect. 2006;8:2640–6. 10.1016/j.micinf.2006.07.009 - DOI - PubMed

Publication types

MeSH terms

LinkOut - more resources