Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1990 Dec:431:505-13.
doi: 10.1113/jphysiol.1990.sp018343.

Permeability of the human placenta in vivo to four non-metabolized hydrophilic molecules

M D Bain  1 , D K Copas, A Taylor, M J Landon, T E Stacey
Affiliations

Permeability of the human placenta in vivo to four non-metabolized hydrophilic molecules

M D Bain et al. J Physiol. 1990 Dec.

Abstract

1. Permeability of the human placenta to four permeants of different molecular size was measured at Caesarean section in seven normal full-term pregnancies. 2. Placental clearance for mannitol was 8.7 +/- 1.1 ml min-1 (mean +/- S.E.M.), lactulose 6.3 +/- 0.8, chromium ethylenediaminetetraacetic acid (CrEDTA) 3.7 +/- 0.5, and inulin 0.98 +/- 0.1. 3. The permeability data were analysed in terms of restricted diffusion through 'notional' water-filled pores and found to be incompatible with a single population of uniform pores.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. J Physiol. 1983 Mar;336:13-26 - PubMed
    1. Placenta. 1980 Oct-Dec;1(4):277-85 - PubMed
    1. Br Med J (Clin Res Ed). 1986 Jul 5;293(6538):17-8 - PubMed
    1. Am J Obstet Gynecol. 1988 May;158(5):1165-9 - PubMed
    1. J Physiol. 1988 May;399:313-9 - PubMed

LinkOut - more resources