Human immunodeficiency virus type 2 in two Saudi families
- PMID: 21293067
- PMCID: PMC3156521
- DOI: 10.4103/0256-4947.76408
Human immunodeficiency virus type 2 in two Saudi families
Abstract
Human immunodeficiency virus type 2 (HIV-2), the second retrovirus that causes the acquired immune deficiency syndrome (AIDS) in humans, is limited in its distribution to West Africa. We report cases in two Saudi families with HIV-2 infection and AIDS, resulting in death of the index cases-the husbands, while the wives and a daughter were maintained on antiretroviral therapy. When HIV viral loads were undetectable in initial assays, further testing confirmed the presence of HIV-2. In the first family, the 30-year-old wife was found to be HIV-positive after the diagnosis in her 30-year-old husband, who later died with AIDS. In the second family, HIV-2 infection was diagnosed in the 50-year-old wife and 18-year-old daughter of a man who had died of AIDS at the age of 48 years. Recognizing HIV-2 infection is essential for appropriate workup, assessment, therapy and care of the pregnant woman.
References
-
- Arya SK, Beaver B, Jagodzinski L, Ensoli B, Kanki PJ, Albert J, et al. New human and simian HIV-related retroviruses possess functional transactivator (tat) gene. Nature. 1987;328:548–50. - PubMed
-
- Schim van der Loeff MF, Aaby P. Towards a better understanding of the epidemiology of HIV-2. AIDS. 1999;13:S69–84. - PubMed
-
- Kanki P, M’Boup S, Marlink R, Travers K, Hsieh CC, Gueye A, et al. Prevalence and risk determinants of human immunodeficiency virus type 2 (HIV-2) and human immunodeficiency virus type 1 (HIV-1) in west African female prostitutes. Am J Epidemiol. 1992;136:895–907. - PubMed
-
- Gilbert PB, McKeague IW, Eisen G, Mullins C, Guéye-NDiaye A, Mboup S, et al. Comparison of HIV-1 and HIV-2 infectivity from a prospective cohort study in Senegal. Stat Med. 2003;22:573–93. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
