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Comment
. 2011 Feb 4;144(3):323-4.
doi: 10.1016/j.cell.2011.01.018.

Need tension relief fast? Try caveolae

Satyajit Mayor  1
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Free article
Comment

Need tension relief fast? Try caveolae

Satyajit Mayor. Cell. .
Free article

Abstract

Caveolae are protein-driven membrane invaginations that regulate both the physical and chemical composition of the plasma membrane. Sinha et al. (2011) now show that caveolae are membrane reservoirs that are used to rapidly buffer against changes in membrane tension.

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  • Cells respond to mechanical stress by rapid disassembly of caveolae.
    Sinha B, Köster D, Ruez R, Gonnord P, Bastiani M, Abankwa D, Stan RV, Butler-Browne G, Vedie B, Johannes L, Morone N, Parton RG, Raposo G, Sens P, Lamaze C, Nassoy P. Sinha B, et al. Cell. 2011 Feb 4;144(3):402-13. doi: 10.1016/j.cell.2010.12.031. Cell. 2011. PMID: 21295700 Free PMC article.

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