Comment
doi: 10.1016/j.cub.2010.12.030.
Chromosome segregation: keeping kinetochores in the loop
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- PMID: 21300272
- DOI: 10.1016/j.cub.2010.12.030
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Comment
Chromosome segregation: keeping kinetochores in the loop
Curr Biol.
.
Free article
Abstract
The Ndc80 complex is a key component of the kinetochore-microtubule interface. Two studies now demonstrate that a conserved loop region within the extended coiled-coil of Ndc80 plays an unexpected role in recruiting proteins to the kinetochore.
Copyright © 2011 Elsevier Ltd. All rights reserved.
Comment on
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The Ndc80 loop region facilitates formation of kinetochore attachment to the dynamic microtubule plus end.Curr Biol. 2011 Feb 8;21(3):207-13. doi: 10.1016/j.cub.2010.12.050. Epub 2011 Jan 20. Curr Biol. 2011. PMID: 21256019 Free PMC article.
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Ndc80 internal loop interacts with Dis1/TOG to ensure proper kinetochore-spindle attachment in fission yeast.Curr Biol. 2011 Feb 8;21(3):214-20. doi: 10.1016/j.cub.2010.12.048. Epub 2011 Jan 20. Curr Biol. 2011. PMID: 21256022 Free PMC article.
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