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Clinical Trial
. 2011 Nov;85(2):e33-8.
doi: 10.1016/j.pec.2011.01.016. Epub 2011 Feb 5.

Who listens to our advice? A secondary analysis of data from a clinical trial testing an intervention designed to decrease delay in seeking treatment for acute coronary syndrome

Barbara Riegel  1 , Angelo Elmi, Debra K Moser, Sharon McKinley, Hendrika Meischke, Lynn V Doering, Patricia Davidson, Michele Pelter, Heather Baker, Kathleen Dracup
Affiliations
Clinical Trial

Who listens to our advice? A secondary analysis of data from a clinical trial testing an intervention designed to decrease delay in seeking treatment for acute coronary syndrome

Barbara Riegel et al. Patient Educ Couns. 2011 Nov.

Abstract

Objective: Prolonged prehospital delay in persons experiencing acute coronary syndrome (ACS) remains a problem. Understanding which patients respond best to particular interventions designed to decrease delay time would provide mechanistic insights into the process by which interventions work.

Methods: In the PROMOTION trial, 3522 at-risk patients were enrolled from 5 sites in the United States (56.4%), Australia and New Zealand; 490 (N=272 intervention, N=218 control) had an acute event within 2 years. Focusing on these 490, we (1) identified predictors of a rapid response to symptoms, (2) identified intervention group subjects with a change in these predictors over 3 months of follow-up, and (3) compared intervention group participants with and without the favorable response pattern. Hypothesized predictors of rapid response were increased perceived control and decreased anxiety. Knowledge, attitudes, and beliefs were hypothesized to differ between responders and non-responders.

Results: Contrary to hypothesis, responders had low anxiety and low perceived control. Only 73 (26.8%) subjects showed this pattern 3 months following the intervention. No differences in ACS knowledge, attitudes, or beliefs were found.

Conclusion: The results of this study challenge existing beliefs.

Practice implications: New intervention approaches that focus on a realistic decrease in anxiety and perceived control are needed.

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Figures

Figure 1
Figure 1
Graphic Depiction of the Manner in which Anxiety and Perceived Control were Hypothesized to Interact to Influence Treatment-Seeking Delay
See this image and copyright information in PMC

References

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