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. 1978 Dec;7(1):337-47.
doi: 10.1007/BF01844023.

Relationship of F9 antigen and genes of theT/t complex

P Marticorena  1 , K Artzt, D Bennett
Affiliations

Relationship of F9 antigen and genes of theT/t complex

P Marticorena et al. Immunogenetics. 1978 Dec.

Abstract

Serological studies relating F9 antigen of embryonal carcinoma cells to[Formula: see text] at the murineT/t complex have been extended and confirm that only the lethal haplotype t(12)- and none of the other five lethal haplotypes-affects the quantitative expression of F9 antigen on sperm. Cytotoxicity tests on preimplantation embryos show that t(12) homozygotes are less susceptible to antiF9 serum than t(w5) homozygotes, and that using specific antimutant haplotype antisera prepared against sperm, t(12) antigen is detectable on morulae, whereas t(w5) antigen is not.

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