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. 2010:65 Spec no.:29-34.

[MALDI-TOF mass spectrometry in clinical bacteriology or how to identify a bacteria within one minute]

[Article in French]
J Descy  1 , C Meex, P Melin, M P Hayette, P Huynen, P De Mol
Affiliations
  • PMID: 21302518
Free article

[MALDI-TOF mass spectrometry in clinical bacteriology or how to identify a bacteria within one minute]

[Article in French]
J Descy et al. Rev Med Liege. 2010.
Free article

Abstract

The major application of MALDI-TOF mass spectrometry in clinical microbiology is the bacterial identification based on the analysis of all their proteins (ribosomal and membrane-associated proteins). This technology allows the identification of most of bacteria within a few minutes. The method is fast, accurate, reliable and cost-effective by comparison to conventional phenotypic techniques. Other applications of MALDI-TOF mass spectrometry are still under development, as the detection of bacterial toxins or resistance mechanisms to antimicrobial agents.

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