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Complete genome sequence of Brachybacterium faecium type strain (Schefferle 6-10)

Alla Lapidus et al. Stand Genomic Sci. .

Abstract

Brachybacterium faecium Collins et al. 1988 is the type species of the genus, and is of phylogenetic interest because of its location in the Dermabacteraceae, a rather isolated family within the actinobacterial suborder Micrococcineae. B. faecium is known for its rod-coccus growth cycle and the ability to degrade uric acid. It grows aerobically or weakly anaerobically. The strain described in this report is a free-living, nonmotile, Gram-positive bacterium, originally isolated from poultry deep litter. Here we describe the features of this organism, together with the complete genome sequence, and annotation. This is the first complete genome sequence of a member of the actinobacterial family Dermabacteraceae, and the 3,614,992 bp long single replicon genome with its 3129 protein-coding and 69 RNA genes is part of the Genomic Encyclopedia of Bacteria and Archaea project.

Keywords: Dermabacteraceae; aerobic; free-living; mesophile; non-pathogenic; rod-coccus growth cycle; uric acid degradation.

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Figures

Figure 1
Figure 1
Phylogenetic tree of B. faecium Schefferle 6-10T and all type strains of the genus Brachybacterium, inferred from 1408 aligned characters [2] of the 16S rRNA sequence under the maximum likelihood criterion [3,4]. The tree was rooted with Dermabacter hominis, another member of the family Dermabacteraceae. The branches are scaled in terms of the expected number of substitutions per site. Numbers above branches are support values from 1000 bootstrap replicates, if larger than 60%. Strains with a genome-sequencing project registered in GOLD [5] are printed in blue; published genomes in bold.
Figure 2
Figure 2
Scanning electron micrograph of B. faecium Schefferle 6-10T
Figure 3
Figure 3
Graphical circular map of the genome. From outside to the center: Genes on forward strand (color by COG categories), Genes on reverse strand (color by COG categories), RNA genes (tRNAs green, rRNAs red, other RNAs black), GC content, GC skew.
Figure 4
Figure 4
Schematic cellular overview of all pathways of the B. faecium strain Schefferle 6-10T metabolism. Nodes represent metabolites, with shape indicating class of metabolite. Lines represent reactions.
See this image and copyright information in PMC

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