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Complete genome sequence of Beutenbergia cavernae type strain (HKI 0122)

Miriam Land et al. Stand Genomic Sci. .

Abstract

Beutenbergia cavernae (Groth et al. 1999) is the type species of the genus and is of phylogenetic interest because of its isolated location in the actinobacterial suborder Micrococcineae. B. cavernae HKI 0122(T) is a Gram-positive, non-motile, non-spore-forming bacterium isolated from a cave in Guangxi (China). B. cavernae grows best under aerobic conditions and shows a rod-coccus growth cycle. Its cell wall peptidoglycan contains the diagnostic L-lysine ← L-glutamate interpeptide bridge. Here we describe the features of this organism, together with the complete genome sequence, and annotation. This is the first completed genome sequence from the poorly populated micrococcineal family Beutenbergiaceae, and this 4,669,183 bp long single replicon genome with its 4225 protein-coding and 53 RNA genes is part of the Genomic Encyclopedia of Bacteria and Archaea project.

Keywords: MK-8(H4); Micrococcineae; actinomycete; aerobic and microaerophilic; mesophile; non-pathogenic; rod-coccus growth cycle.

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Figures

Figure 1
Figure 1
Phylogenetic tree of B. cavernae HKI 0122T and all type strains of the genus Beutenbergia, inferred from 1411 aligned characters [5,6] of the 16S rRNA sequence under the maximum likelihood criterion [7]. The tree was rooted with species from the genera Isoptericola and Oerskovia, both also members of the actinobacterial suborder Micrococcineae. The branches are scaled in terms of the expected number of substitutions per site. Numbers above branches are support values from 1000 bootstrap replicates if larger than 60%. Strains with a genome-sequencing project registered in GOLD [8] are printed in blue; published genomes in bold.
Figure 2
Figure 2
Scanning electron micrograph of B. cavernae HKI 0122T
Figure 3
Figure 3
Graphical circular map of the genome. From outside to the center: Genes on forward strand (color by COG categories), Genes on reverse strand (color by COG categories), RNA genes (tRNAs green, rRNAs red, other RNAs black), GC content, GC skew
See this image and copyright information in PMC

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