The role of adenovirus in respiratory tract infections
- PMID: 21308503
- PMCID: PMC7089177
- DOI: 10.1007/s11908-010-0084-5
The role of adenovirus in respiratory tract infections
Abstract
Adenovirus plays a significant role in respiratory tract disease in pediatric and adult patients. It has been linked to outbreaks and epidemics in various patient populations, resulting in considerable morbidity and mortality. In this article, we discuss the epidemiology, pathogenesis, respiratory tract illnesses and complications, and roles of potential treatment options. The role of the past oral adenovirus vaccine and the military implications of its withdrawal from routine use in military recruits is discussed as well.
Figures
References
-
- Woodward TE: The Armed Forces Epidemiological Board: Its First Fifty Years. Falls Church, VA: Center of Excellence in Military Medical Research and Education, Office of the Surgeon General, Department of the Army; 1994. Available at http://history.amedd.army.mil/booksdocs/itsfirst50yrs/fiftyyears.html.
-
- Mandell GL, Bennett JE, Dolin R. Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases. 7. Philadelphia: Elsevier; 2009.
-
- Rowe WP, Huebner RJ, Gillmore LK, et al. Isolation of a cytopathogenic agent from human adenoids undergoing spontaneous degeneration in tissue culture. Proc Soc Exp Biol Med. 1953;84:570–573. - PubMed
-
- Brandt CD, Kim HW, Vargosko AJ, et al. Infections in 18,000 infants and children in a controlled study of respiratory tract disease. I. Adenovirus pathogenicity in relation to serologic type and illness syndrome. Am J Epidemol. 1969;90:484–500. - PubMed
-
- Hale GA, Heslop HE, Krance RA, et al. Adenovirus infection after pediatric bone marrow transplantation. Bone Marrow Transplant. 1999;23:277–282. - PubMed
LinkOut - more resources
Full Text Sources
Miscellaneous
