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Review
. 2011 May 30;63(6):456-69.
doi: 10.1016/j.addr.2011.02.001. Epub 2011 Feb 21.

Physical and chemical stability of drug nanoparticles

Libo Wu  1 , Jian Zhang, Wiwik Watanabe
Affiliations
Review

Physical and chemical stability of drug nanoparticles

Libo Wu et al. Adv Drug Deliv Rev. .

Abstract

As nano-sizing is becoming a more common approach for pharmaceutical product development, researchers are taking advantage of the unique inherent properties of nanoparticles for a wide variety of applications. This article reviews the physical and chemical stability of drug nanoparticles, including their mechanisms and corresponding characterization techniques. A few common strategies to overcome stability issues are also discussed.

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