Mitochondrial fusion: bax to the fussure
- PMID: 21316581
- DOI: 10.1016/j.devcel.2011.01.016
Mitochondrial fusion: bax to the fussure
Abstract
Mitochondria can be organized into highly interconnected networks through continuous cycles of fission and fusion. A recent study by Hoppins et al. (2011) published in Molecular Cell now suggests that Bax, more commonly known for its role in apoptosis, can promote mitochondrial fusion in a Mitofusin 2-dependent manner.
Copyright © 2011 Elsevier Inc. All rights reserved.
Comment on
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The soluble form of Bax regulates mitochondrial fusion via MFN2 homotypic complexes.Mol Cell. 2011 Jan 21;41(2):150-60. doi: 10.1016/j.molcel.2010.11.030. Mol Cell. 2011. PMID: 21255726 Free PMC article.
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