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. 2011 Mar;52(2):347-50.
doi: 10.3349/ymj.2011.52.2.347.

Serum anti-Saccharomyces cerevisiae antibodies in Greek patients with Behcet's disease

George Vaiopoulos  1 , Peter Laszlo Lakatos, Maria Papp, Faedon Kaklamanis, Efrosyni Economou, Vassilis Zevgolis, John Sourdis, Kostas Konstantopoulos
Affiliations

Serum anti-Saccharomyces cerevisiae antibodies in Greek patients with Behcet's disease

George Vaiopoulos et al. Yonsei Med J. 2011 Mar.

Abstract

We tested 59 Greek patients with Behcet's Disease (BD) for serum anti-Saccharomyces cerevisiae antibodies. No increase of these antibodies was detected in the cases compared to 55 healthy unrelated blood donors from the same population. This finding is in contrast with the correlation between Saccharomyces cerevisiae antibodies and BD as reported in other populations. It seems that environmental factors may contribute to disease expression in different populations, producing different effects according to the individual's genetic predisposition. Saccharomyces cerevisiae antibodies do not seem to be of any significance in the Greek population.

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Conflict of interest statement

The authors have no financial conflicts of interest.

Figures

Fig. 1
Fig. 1
Distribution of IgA and IgG serum ASCA levels in 58 Greek BD patients and 55 healthy blood donors from the same population. ASCA, anti-Saccharomyces cerevisiae antiodies.
See this image and copyright information in PMC

References

    1. Zouboulis CC, Kötter I, Djawari D, Kirch W, Kohl PK, Ochsendorf FR, et al. Epidemiological features of Adamantiades-Behçet's disease in Germany and in Europe. Yonsei Med J. 1997;38:411–422. - PubMed
    1. Ben-Chetrit E, Yazici H. Thoughts on the proposed links between Behçet's disease and familial Mediterranean fever. Clin Exp Rheumatol. 2002;20:S1–S2. - PubMed
    1. Hamuryudan V, Yurdakul S, Yazıcı H. Morbus Behçet. Rheumatology in Europe. 1997;26:31–33.
    1. Lakhanpal S, Tani K, Lie JT, Katoh K, Ishigatsubo Y, Ohokubo T. Pathologic features of Behçet's syndrome: a review of Japanese autopsy registry data. Hum Pathol. 1985;16:790–795. - PubMed
    1. Wright VA, Chamberlain MA. Behçet's syndrome. Bull Rheum Dis. 1978-1979;29:972–979. - PubMed

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