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Comment
. 2011 Feb;11(2):79.

Genomics: driving cancer biology

Gemma K Alderton
  • PMID: 21322290
Comment

Genomics: driving cancer biology

Gemma K Alderton. Nat Rev Cancer. 2011 Feb.

Abstract

A new algorithm that combines gene expression and copy number alterations to identify driver genes and their possible function is reported. This was applied to melanoma samples, and vesicular trafficking was found to be an important process in this type of cancer.

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Comment on

  • An integrated approach to uncover drivers of cancer.
    Akavia UD, Litvin O, Kim J, Sanchez-Garcia F, Kotliar D, Causton HC, Pochanard P, Mozes E, Garraway LA, Pe'er D. Akavia UD, et al. Cell. 2010 Dec 10;143(6):1005-17. doi: 10.1016/j.cell.2010.11.013. Epub 2010 Dec 2. Cell. 2010. PMID: 21129771 Free PMC article.

References

    1. Cell. 2010 Dec 10;143(6):1005-17 - PubMed