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Comment
. 2011 Feb;11(2):79.

Medulloblastoma: origins

Nicola McCarthy
  • PMID: 21322837
Comment

Medulloblastoma: origins

Nicola McCarthy. Nat Rev Cancer. 2011 Feb.

Abstract

Medulloblastomas with a mutation in the Wnt pathway arise from cells that are distinct from those affected by mutations in the SHH pathway.

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Comment on

  • Subtypes of medulloblastoma have distinct developmental origins.
    Gibson P, Tong Y, Robinson G, Thompson MC, Currle DS, Eden C, Kranenburg TA, Hogg T, Poppleton H, Martin J, Finkelstein D, Pounds S, Weiss A, Patay Z, Scoggins M, Ogg R, Pei Y, Yang ZJ, Brun S, Lee Y, Zindy F, Lindsey JC, Taketo MM, Boop FA, Sanford RA, Gajjar A, Clifford SC, Roussel MF, McKinnon PJ, Gutmann DH, Ellison DW, Wechsler-Reya R, Gilbertson RJ. Gibson P, et al. Nature. 2010 Dec 23;468(7327):1095-9. doi: 10.1038/nature09587. Epub 2010 Dec 8. Nature. 2010. PMID: 21150899 Free PMC article.

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