Sr and Ba transients in isolated snail neurones studied with fura-2. The recovery from depolarization induced load and modulation of Ca release from intracellular stores
- PMID: 2132298
- DOI: 10.1016/0304-3940(90)90200-s
Sr and Ba transients in isolated snail neurones studied with fura-2. The recovery from depolarization induced load and modulation of Ca release from intracellular stores
Abstract
The fluorescent Ca-sensitive probe fura-2 was used in isolated non-identified neurons of the snail, Helix pomatia, to study the recovery from Sr and Ba loading and the effect of these cations on Ca-induced Ca release. Sr was shown to behave similarly to Ca, whereas Ba ions were not sequestered within the cell. Intracellular Ba blocked both the voltage-gated channels in the plasma membrane and the Ca release channels in the membrane of intracellular stores.
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