Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011 Jun 30;95(8):2651-4.
doi: 10.1016/j.fertnstert.2011.01.129. Epub 2011 Feb 16.

CD4+CD28 null T lymphocytes are expanded in young women with polycystic ovary syndrome

Giampaolo Niccoli  1 , Rosanna Apa, Antonio Lanzone, Giovanna Liuzzo, Cristina Spaziani, Francesca Sagnella, Nicola Cosentino, Francesca Moro, Daniela Martinez, Andrea Morciano, Marco Bacà, Vincenzo Pazzano, Maria Francesca Gangale, Anna Tropea, Filippo Crea
Affiliations
Free article

CD4+CD28 null T lymphocytes are expanded in young women with polycystic ovary syndrome

Giampaolo Niccoli et al. Fertil Steril. .
Free article

Abstract

Women affected by polycystic ovary syndrome (PCOS) have an increased risk of cardiovascular disease. We demonstrated that women with PCOS showed an expansion of CD4(+)CD28(null) T cells, an aggressive population of T lymphocytes that has been recently associated with recurrent coronary instability and type 2 diabetes mellitus. This sheds new light on possible mechanisms responsible for the higher rate of cardiovascular disease among women with PCOS.

PubMed Disclaimer

MeSH terms