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Clinical Trial
. 2011 Sep 1;117(2-3):118-25.
doi: 10.1016/j.drugalcdep.2010.12.027. Epub 2011 Feb 15.

Within-day temporal patterns of smoking, withdrawal symptoms, and craving

Affiliations
Clinical Trial

Within-day temporal patterns of smoking, withdrawal symptoms, and craving

Siddharth Chandra et al. Drug Alcohol Depend. .

Abstract

We examined the temporal relationships between smoking frequency and craving and withdrawal. 351 heavy smokers (≥15 cigarettes per day) used ecological momentary assessment and electronic diaries to track smoking, craving, negative affect, arousal, restlessness, and attention disturbance in real time over 16 days. The waking day was divided into 8 2-h "bins" during which cigarette counts and mean levels of craving and withdrawal were computed. Cross-sectional analyses showed no association between restlessness and smoking, and arousal and smoking, but craving (b=0.65, p<0.01) was positively associated, and negative affect (b=-0.20, p<0.01), and attention disturbance (b=-0.24, p<0.01) were inversely associated with smoking. In prospective lagged analyses, higher craving predicted more subsequent smoking and higher smoking predicted lower craving (p's<0.01). Higher restlessness also predicted more subsequent smoking and higher smoking predicted lower restlessness (p's<0.01). Higher negative affect did not predict later smoking, but more smoking preceded lower negative affect (p<0.01). Neither attention disturbance nor arousal predicted, or were predicted by variations in smoking. In short, smoking exhibits time-lagged, reciprocal relationships with craving and restlessness, and a one-way predictive relationship with negative affect. Temporal patterns of craving and restlessness may aid in the design of smoking cessation interventions.

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Figures

Figure 1
Figure 1
Daily patterns of (a) smoking, (b) craving and restlessness, (c) negative affect and arousal, and (d) attention disturbance. Times on the X-axis represent approximate times for each of 8 2-hour bins.
Figure 2
Figure 2
Relationships between (a) craving and (b) restlessness and subsequent smoking, based on models described in the text. The range on the X-axis represents the 5th to 95th percentile of observed values.

References

    1. American Psychiatric Association . Diagnostic and Statistical Manual of Mental Health Disorders. Fourth. Washington, DC: 2000. Text Revision.
    1. Baker TB, Piper ME, McCarthy DE, Majeskie MR, Fiore MC. Addiction motivation reformulated: an affective processing model of negative reinforcement. Psychol Rev. 2004;111:33–51. - PubMed
    1. Benowitz NL. Clinical pharmacology of nicotine: implications for understanding, preventing, and treating tobacco addition. Clin Pharmacol Ther. 2008;83:531–541. - PubMed
    1. Carter BL, Lam CY, Robinson JD, Paris MM, Waters AJ, Wetter DW, Cinciripini PM. Real-time craving and mood assessments before and after smoking. Nicotine Tob Res. 2008;10:1165–1169. - PMC - PubMed
    1. Chandra S, Shiffman S, Scharf DM, Dang Q, Shadel WG. Daily smoking patterns, their determinants, and implications for quitting. Exp Clin Psychopharmacol. 2007;15:67–80. - PubMed

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