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. 2011 Apr 7;47(13):3989-91.
doi: 10.1039/c0cc05619g. Epub 2011 Feb 17.

Sequential Birch reaction and asymmetric Ir-catalyzed hydrogenation as a route to chiral building blocks

Alexander Paptchikhine  1 , Kaori Itto, Pher G Andersson
Affiliations

Sequential Birch reaction and asymmetric Ir-catalyzed hydrogenation as a route to chiral building blocks

Alexander Paptchikhine et al. Chem Commun (Camb). .

Abstract

A range of 1,2,4-trisubstituted cyclohexadienes obtained from the Birch reaction were hydrogenated asymmetrically to produce synthetically valuable chiral compounds in high enantio- and diastereoselectivity.

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