Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011 Apr;96(4):631-2.
doi: 10.3324/haematol.2010.037838. Epub 2011 Feb 17.

Influence of residual normal metaphases in acute myeloid leukemia patients with monosomal karyotype

Bin Xie, Megan Othus, Bruno C Medeiros, Min Fang, Frederick R Appelbaum, Elihu H Estey

Influence of residual normal metaphases in acute myeloid leukemia patients with monosomal karyotype

Bin Xie et al. Haematologica. 2011 Apr.
No abstract available

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Overall survival curves estimated by the method of Kaplan-Meier with or without at least one normal metaphase.
See this image and copyright information in PMC

Comment in

References

    1. Byrd JC, Mrozek K, Dodge RK, Carroll AJ, Edwards CG, Arthur DC, et al. Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461) Blood. 2002;100(13):4325–36. - PubMed
    1. Grimwade D, Walker H, Oliver F, Wheatley K, Harrison C, Harrison G, et al. The importance of diagnostic cytogenetics on outcome in AML: analysis of 1,612 patients entered into the MRC AML 10 trial. The Medical Research Council Adult and Children's Leukaemia Working Parties. Blood. 1998;92(7):2322–33. - PubMed
    1. Mrozek K, Bloomfield CD. Chromosome aberrations, gene mutations and expression changes, and prognosis in adult acute myeloid leukemia. Hematology Am Soc Hematol Educ Program. 2006:169–77. - PubMed
    1. Mrozek K, Heerema NA, Bloomfield CD. Cytogenetics in acute leukemia. Blood Rev. 2004;18(2):115–36. - PubMed
    1. Breems DA, Van Putten WL, De Greef GE, Van Zelderen-Bhola SL, Gerssen-Schoorl KB, Mellink CH, et al. Monosomal karyotype in acute myeloid leukemia: a better indicator of poor prognosis than a complex karyotype. J Clin Oncol. 2008;26(29):4791–7. - PubMed