Advances of bioinformatics tools applied in virus epitopes prediction
- PMID: 21331885
- PMCID: PMC7090880
- DOI: 10.1007/s12250-011-3159-4
Advances of bioinformatics tools applied in virus epitopes prediction
Abstract
In recent years, the in silico epitopes prediction tools have facilitated the progress of vaccines development significantly and many have been applied to predict epitopes in viruses successfully. Herein, a general overview of different tools currently available, including T cell and B cell epitopes prediction tools, is presented. And the principles of different prediction algorithms are reviewed briefly. Finally, several examples are present to illustrate the application of the prediction tools.
References
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- Díaz I., Pujols J., Ganges L., et al. In silico prediction and ex vivo evaluation of potential T-cell epitopes in glycoproteins 4 and 5 and nucleocapsid protein of genotype-I (European) of porcine reproductive and respiratory syndrome virus. Vaccine. 2009;27(41):5603–5611. doi: 10.1016/j.vaccine.2009.07.029. - DOI - PubMed
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