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Randomized Controlled Trial
. 2011 May;95(6):1961-5.
doi: 10.1016/j.fertnstert.2011.01.148. Epub 2011 Feb 21.

Comparison of oral dydrogestrone with progesterone gel and micronized progesterone for luteal support in 1,373 women undergoing in vitro fertilization: a randomized clinical study

Ashalatha Ganesh  1 , Nishant Chakravorty, Rashmi Mukherjee, Sourendrakanta Goswami, Koel Chaudhury, Baidyanath Chakravarty
Affiliations
Randomized Controlled Trial

Comparison of oral dydrogestrone with progesterone gel and micronized progesterone for luteal support in 1,373 women undergoing in vitro fertilization: a randomized clinical study

Ashalatha Ganesh et al. Fertil Steril. 2011 May.

Abstract

Objective: To compare the efficacy of oral dydrogesterone with that of micronized vaginal P gel and micronized P capsule for luteal supplementation.

Design: Prospective, randomized clinical study.

Setting: Institute of Reproductive Medicine, Kolkata, India.

Patient(s): A total of 1,373 infertile women undergoing IVF participated.

Intervention(s): Micronized P gel, P capsule, and oral dydrogesterone were administered for luteal support and compared.

Main outcome measure(s): Demographic profile and pregnancy and miscarriage rates.

Result(s): The overall pregnancy rate and miscarriage rate were comparable among the three groups.

Conclusion(s): Oral dydrogesterone seems to be a promising drug for luteal support in woman undergoing IVF.

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