doi: 10.1136/jcp.31.10.933.
Incomplete anaerobiosis as a cause of metronidazole 'resistance'
- PMID: 213449
- PMCID: PMC1145454
- DOI: 10.1136/jcp.31.10.933
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Incomplete anaerobiosis as a cause of metronidazole 'resistance'
J Clin Pathol.
1978 Oct.
Abstract
Clostridium welchii, used as a control, was found to grow well in a microaerophilic jar used for campylobacters but appeared resistant to a metronidazole disc although the campylobacter was sensitive. Minimum inhibitory concentrations for six strains of Cl. welchii were up to 64-fold higher in these conditions than when grown anaerobically. Zones of inhibition with both Cl. welchii and Bacteroides fragilis varied with the amount of air admitted to anaerobic jars.
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References
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- J Clin Pathol. 1977 Nov;30(11):1028-9 - PubMed
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