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Comparative Study
. 1990 Nov;102(1):41-73.
doi: 10.1016/0025-5564(90)90055-4.

Global identifiability of the parameters of nonlinear systems with specified inputs: a comparison of methods

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Comparative Study

Global identifiability of the parameters of nonlinear systems with specified inputs: a comparison of methods

M J Chappell et al. Math Biosci. 1990 Nov.

Abstract

The two methods available for analyzing the global structural identifiability of the parameters of a nonlinear system with a specified input function, the Taylor series approach and the similarity transformation approach, are compared and contrasted through application to three examples. It is shown that, as for linear systems, it is very difficult to predict which of the available methods will result in the least effort for a particular example. The role of modern symbolic manipulation packages in the analysis is assessed. The third example proves intractable using the similarity transformation approach as originally formulated, but the analysis is completed using a reformulation that exploits the polynominal form of the system equations in the example.

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