Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2011;15(1):112.
doi: 10.1186/cc9405. Epub 2011 Jan 26.

Too early initiation of renal replacement therapy may be harmful

Affiliations
Comment

Too early initiation of renal replacement therapy may be harmful

Christophe Vinsonneau et al. Crit Care. 2011.

Abstract

In an observational multicenter study, Elseviers and colleagues report that renal replacement therapy (RRT) in acutely ill patients treated for acute kidney injury is an independent risk factor for death. This result may question the benefit of the current practice of early RRT initiation.

PubMed Disclaimer

Comment on

References

    1. Elseviers MM, Lins RL, Van der Niepen P, Hoste E, Malbrain ML, Damas P, Devriendt J. (SHARF) Investigators SHARF. Renal replacement therapy is an independent risk factor for mortality in critically ill patients with acute kidney injury. Crit Care. 2010;14:R221. doi: 10.1186/cc9355. - DOI - PMC - PubMed
    1. Joannidis M, Metnitz B, Bauer P, Schusterschitz N, Moreno R, Druml W, Metnitz PG. Acute kidney injury in critically ill patients classified by AKIN versus RIFLE using the SAPS 3database. Intensive Care Med. 2009;35:1692–1702. doi: 10.1007/s00134-009-1530-4. - DOI - PubMed
    1. Coca SG, Peixoto AJ, Garg AX, Krumholz H, Parikh CR. The prognostic importance of a small acute decrement in kidney function in hospitalized patients: a systematic review and meta-analysis. Am J Kidney Dis. 2007;50:712–720. doi: 10.1053/j.ajkd.2007.07.018. - DOI - PubMed
    1. Metnitz PG, Krenn CG, Steltzer H, Lang T, Ploder J, Lenz K, Le Gall JR, Druml W. Effects of acute renal failure requiring renal replacement therapy on outcome in critically ill patients. Crit Care Med. 2002;30:2051–2058. doi: 10.1097/00003246-200209000-00016. - DOI - PubMed
    1. Guerin C, Girard R, Selli JM, Perdrix JP, Ayzac L. Initial versus delayed acute renal failure in the intensive care unit. Am J Respir Crit Care Med. 2000;161:872–879. - PubMed