Too early initiation of renal replacement therapy may be harmful
- PMID: 21345253
- PMCID: PMC3222035
- DOI: 10.1186/cc9405
Too early initiation of renal replacement therapy may be harmful
Abstract
In an observational multicenter study, Elseviers and colleagues report that renal replacement therapy (RRT) in acutely ill patients treated for acute kidney injury is an independent risk factor for death. This result may question the benefit of the current practice of early RRT initiation.
Comment on
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Renal replacement therapy is an independent risk factor for mortality in critically ill patients with acute kidney injury.Crit Care. 2010;14(6):R221. doi: 10.1186/cc9355. Epub 2010 Dec 1. Crit Care. 2010. PMID: 21122146 Free PMC article.
References
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- Elseviers MM, Lins RL, Van der Niepen P, Hoste E, Malbrain ML, Damas P, Devriendt J. (SHARF) Investigators SHARF. Renal replacement therapy is an independent risk factor for mortality in critically ill patients with acute kidney injury. Crit Care. 2010;14:R221. doi: 10.1186/cc9355. - DOI - PMC - PubMed
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- Guerin C, Girard R, Selli JM, Perdrix JP, Ayzac L. Initial versus delayed acute renal failure in the intensive care unit. Am J Respir Crit Care Med. 2000;161:872–879. - PubMed
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