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Review

Comparative Effectiveness of Angiotensin-Converting Enzyme Inhibitors (ACEIs) and Angiotensin II Receptor Antagonists (ARBs) for Treating Essential Hypertension [Internet]

David B Matchar  1 , Douglas C McCrory  1 , Lori A Orlando  1 , Manesh R Patel  1 , Uptal D Patel  1 , Meenal B Patwardhan  1 , Benjamin Powers  1 , Gregory P Samsa  1 , Rebecca N Gray  1
Rockville (MD): Agency for Healthcare Research and Quality (US); 2007 Nov. Report No.: 08-EHC003-EF.
AHRQ Comparative Effectiveness Reviews.
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Free Books & Documents
Review

Comparative Effectiveness of Angiotensin-Converting Enzyme Inhibitors (ACEIs) and Angiotensin II Receptor Antagonists (ARBs) for Treating Essential Hypertension [Internet]

David B Matchar et al.
Free Books & Documents

Excerpt

In this comparative effectiveness review, we examine the scientific literature on angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II receptor antagonists (ARBs, or angiotensin receptor blockers) for individuals with hypertension regarding their relative benefits (blood pressure control, cardiovascular risk reduction, cardiovascular events, quality of life, and other outcomes), as well as relative risks (safety, adverse events, tolerability, persistence, and adherence). In addition, we will examine the clinical determinants of these outcomes with a focus on the long-term impact.

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Prepared for: Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services. Contract No. 290-02-0025. Prepared by: Duke Evidence-based Practice Center.

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