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Review

EBV-induced oncogenesis

Nancy Raab-Traub  1
Ann Arvin  1 , Gabriella Campadelli-Fiume  2 , Edward Mocarski  3 , Patrick S. Moore  4 , Bernard Roizman  5 , Richard Whitley  6 , Koichi Yamanishi  7
, editors.
In: Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis. Cambridge: Cambridge University Press; 2007. Chapter 55.
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Review

EBV-induced oncogenesis

Nancy Raab-Traub.
Free Books & Documents

Excerpt

The Epstein–Barr virus (EBV) is a human herpesvirus that is a ubiquitous infectious agent, infecting greater than 90% of the world’s population (Henle et al., 1969). The majority of infections occur early in life without significant illness. However, EBV is clearly an important factor in multiple human cancers. This dichotomy raises the question as to what are the unique aspects of infection in those who develop cancers. The study of EBV and its associated tumors points to specific interactions between environmental, genetic, and viral factors.

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References

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