Standing guard at the mucosa
- PMID: 21349427
- DOI: 10.1016/j.immuni.2011.02.014
Standing guard at the mucosa
Abstract
Most successful vaccines elicit antibodies that protect against infection. In this issue of Immunity, Bomsel et al. (2011) show in the rhesus macaque model that vaccine-induced mucosal antibodies, rather than circulating neutralizing antibodies, may be critical components for protective immunity against HIV-1.
Copyright © 2011 Elsevier Inc. All rights reserved.
Comment on
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Immunization with HIV-1 gp41 subunit virosomes induces mucosal antibodies protecting nonhuman primates against vaginal SHIV challenges.Immunity. 2011 Feb 25;34(2):269-80. doi: 10.1016/j.immuni.2011.01.015. Immunity. 2011. PMID: 21315623
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