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Comment
. 2011 Feb 24;470(7335):470-1.
doi: 10.1038/470470a.

Prion diseases: Infectivity versus toxicity

Comment

Prion diseases: Infectivity versus toxicity

Reed B Wickner. Nature. .
No abstract available

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Figures

Figure 1
Figure 1
Sandberg et al. show that, irrespective of how much PrP a mouse line produces normally, all lines reach the same plateau of infectivity after inoculation with infectious PrP. However, the amount of PrP an animal produces affects how soon it will die after the infectivity plateau is reached. (Adapted from ref. .)

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References

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