Shining a light on energy homeostasis
- PMID: 21356511
- PMCID: PMC3073614
- DOI: 10.1016/j.cmet.2011.02.007
Shining a light on energy homeostasis
Abstract
The hypothalamic arcuate nucleus is a complex structure containing both orexigenic and anorexigenic neurons, coordinately regulated by leptin and energy state. In their recent Nature Neuroscience study, Aponte et al. (2011) use optogenetic technology to provide a glimpse into the consequences of exclusive activation of either NPY/AgRP or POMC neurons.
Copyright © 2011 Elsevier Inc. All rights reserved.
Comment on
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AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training.Nat Neurosci. 2011 Mar;14(3):351-5. doi: 10.1038/nn.2739. Epub 2010 Jan 5. Nat Neurosci. 2011. PMID: 21209617 Free PMC article.
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