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. 2011 Mar;8(3):221-9.
doi: 10.1038/nmeth.1570.

A primer to scaffolded DNA origami

Carlos Ernesto Castro  1 , Fabian Kilchherr, Do-Nyun Kim, Enrique Lin Shiao, Tobias Wauer, Philipp Wortmann, Mark Bathe, Hendrik Dietz
Affiliations

A primer to scaffolded DNA origami

Carlos Ernesto Castro et al. Nat Methods. 2011 Mar.

Abstract

Molecular self-assembly with scaffolded DNA origami enables building custom-shaped nanometer-scale objects with molecular weights in the megadalton regime. Here we provide a practical guide for design and assembly of scaffolded DNA origami objects. We also introduce a computational tool for predicting the structure of DNA origami objects and provide information on the conditions under which DNA origami objects can be expected to maintain their structure.

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