[Skin Barrier creams for protection against aqueous solutions of chromium and nickel compounds]

Abstract

The purpose of the investigation was to evaluate the efficiency of two protective creams elaborated in my laboratory, devised for protection of skin exposed to aqueous solution of chromium and nickel compounds. The creams were tested by the measurement of Cr2O7(2-) and Ni2+ absorption rate through the skin in rats and excretion of these metals in urine after termination of exposure. It was found that absorption rate both ions through the skin and their excretion in urine decreased in presence of creams. However, correlation between absorption rate and excretion of these metals in urine was not found.