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Comment
. 2011 Mar 4;8(3):242-4.
doi: 10.1016/j.stem.2011.02.015.

Clever leukemic stem cells branch out

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Clever leukemic stem cells branch out

Paresh Vyas et al. Cell Stem Cell. .
Free article

Abstract

Individual tumors harbor heterogeneous populations of genetically distinct subclones. Two recent papers in Nature by Notta et al. (2011) and Anderson et al. (2011) reveal genetic heterogeneity in functional leukemic stem cells, which has important implications for how both cancer and normal stem cell populations may adapt to selective pressure.

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