Health economics of dengue: a systematic literature review and expert panel's assessment
- PMID: 21363989
- PMCID: PMC3042827
- DOI: 10.4269/ajtmh.2011.10-0521
Health economics of dengue: a systematic literature review and expert panel's assessment
Abstract
Dengue vaccines are currently in development and policymakers need appropriate economic studies to determine their potential financial and public health impact. We searched five databases (PubMed, EMBASE, LILAC, EconLit, and WHOLIS) to identify health economics studies of dengue. Forty-three manuscripts were identified that provided primary data: 32 report economic burden of dengue and nine are comparative economic analyses assessing various interventions. The remaining two were a willingness-to-pay study and a policymaker survey. An expert panel reviewed the existing dengue economic literature and recommended future research to fill information gaps. Although dengue is an important vector-borne disease, the economic literature is relatively sparse and results have often been conflicting because of use of inconsistent assumptions. Health economic research specific to dengue is urgently needed to ensure informed decision making on the various options for controlling and preventing this disease.
Conflict of interest statement
Disclosure: LC is an employee of Sanofi Pasteur, a company that is currently developing a dengue vaccine. This statement is made in the interest of full disclosure and not because the authors consider this to be a conflict of interest.
Figures
References
-
- Scientific Working Group on Dengue . Report of the Scientific Working Group on Dengue, 1–5 October 2006. Geneva: World Health Organization; 2007.
-
- Guy B, Nougarede N, Begue S, Sanchez V, Souag N, Carre M, Chambonneau L, Morrisson DN, Shaw D, Qiao M, Dumas R, Lang J, Forrat R. Cell-mediated immunity induced by chimeric tetravalent dengue vaccine in naive or flavivirus-primed subjects. Vaccine. 2008;26:5712–5721. - PubMed
-
- Sun W, Cunningham D, Wasserman SS, Perry J, Putnak JR, Eckels KH, Vaughn DW, Thomas SJ, Kanesa-Thasan N, Innis BL, Edelman R. Phase 2 clinical trial of three formulations of tetravalent live-attenuated dengue vaccine in flavivirus-naive adults. Hum Vaccine. 2008;4:33–40. - PubMed
-
- Widdus R. Public-private partnerships: an overview. Trans R Soc Trop Med Hyg. 2005;99((Suppl 1)):S1–S8. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
