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. 2011 Mar;10(3):M110.006387.
doi: 10.1074/mcp.M110.006387.

Interpretation of data underlying the link between colony collapse disorder (CCD) and an invertebrate iridescent virus

Leonard J Foster  1
Affiliations

Interpretation of data underlying the link between colony collapse disorder (CCD) and an invertebrate iridescent virus

Leonard J Foster. Mol Cell Proteomics. 2011 Mar.
No abstract available

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Figures

Fig. 1.
Fig. 1.
Missed cleavages in peptides. A large-scale honey bee LC-MS/MS dataset was acquired on an LTQ-OrbitrapXL as described (5) and searched using MaxQuant against two different protein libraries: (1) all Apis mellifera protein sequences plus sequences from Israeli Acute Paralysis Virus, Kashmir Bee Virus, Black Queen Cell Virus, Invertebrate Iridescent Virus 6, Deformed Wing Virus, and Acute Bee Paralysis Virus, or (2) just the above mentioned virus sequences. The number of missed trypsin cleavages (defined as the count of internal R or K residue except those followed by a P) was then evaluated in the results from these two searches (black bars for search #1, dark grey bars for search #2), as well as the list of peptides provided by Bromenshenk et al. (light grey bars).
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References

    1. Bromenshenk J. J., Henderson C. B., Wick C. H., Stanford M. F., Zulich A. W., Jabbour R. E., Deshpande S. V., McCubbin P. E., Seccomb R. A., Welch P. M., Williams T., Firth D. R., Skowronski E., Lehmann M. M., Bilimoria S. L., Gress J., Wanner K. W., Cramer R. A., Jr. (2010) Iridovirus and microsporidian linked to honey bee colony decline. PLoS One 5, e13181. - PMC - PubMed
    1. Ince I. A., Boeren S. A., van Oers M. M., Vervoort J. J., Vlak J. M. (2010) Proteomic analysis of chilo iridescent virus. Virology 405, 253–258 - PMC - PubMed
    1. Olsen J. V., Ong S. E., Mann M. (2004) Trypsin cleaves exclusively C-terminal to arginine and lysine residues. Mol Cell Proteomics 3, 608–614 - PubMed
    1. Cargile B. J., Bundy J. L., Stephenson J. L., Jr. (2004) Potential for false positive identifications from large databases through tandem mass spectrometry. J Proteome Res 3, 1082–1085 - PubMed
    1. Parker R., Melathopoulos A. P., White R., Pernal S. F., Guarna M. M., Foster L. J. (2010) Ecological adaptation of diverse honey bee (apis mellifera) populations. PLoS ONE 5, e11096. - PMC - PubMed