Shortcuts to making cardiomyocytes
- PMID: 21364566
- DOI: 10.1038/ncb0311-191
Shortcuts to making cardiomyocytes
Abstract
The adult human heart lacks sufficient regenerative capacity to recover after a myocardial infarction. Cell-based therapy has emerged as a potential treatment for the failing heart; however, a key issue for the success of future cell-based therapies is the ability to obtain patient-specific high-quality cardiomyocytes in a fast and efficient manner. Recent progress has been made towards this goal using reprogramming-based approaches.
© 2011 Macmillan Publishers Limited. All rights reserved
Comment on
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Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy.Nat Cell Biol. 2011 Mar;13(3):215-22. doi: 10.1038/ncb2164. Epub 2011 Jan 30. Nat Cell Biol. 2011. PMID: 21278734
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