[Functional cerebral activity in a state of rest: connectivity networks]

Abstract

Functional connectivity can be measured during task-based functional magnetic resonance imaging (fMRI), or in the absence of specific stimuli or tasks. In either case, the study of low frequency fluctuations in the BOLD signal reveals patterns of synchronization which delineate the intrinsic functional architecture of the brain. The scientific community now has available shared resources to accelerate the exploitation of resting state fMRI with the objectives of improving diagnostic methods and leading to better treatments grounded in neuroscience. Fomenting a collaborative scientific culture will accelerate our understanding of the underlying phenonmemna. Recently, the Spanish Resting State Network (SRSN) has joined this collaborative effort by creating a setting to facilitate collaboration among the various neuroscience research groups working in Spanish (http://www.nitrc.org/projects/srsn).

Pie de Figura 1

Muestra el circuito motor como se puede obtener en cualquier laboratorio por medio de la RMf-tarea motora inducida (ejemplo obtenido en Servicio de Radiología, Hospital Quirón de Valencia, España y gracias a la participación de Gracian Garcia). Esta imagen muestra la similitud con el hallazgo original de Biswal et al., 1995 en donde se muestran las correlaciones de un ROI en la corteza motriz realizando RMf-reposo.