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. 2010 Oct;26(4):480-9.
doi: 10.4103/0970-1591.74434.

Etiopathogenesis and management of bladder dysfunction in patients with posterior urethral valves

Joseph Thomas  1
Affiliations

Etiopathogenesis and management of bladder dysfunction in patients with posterior urethral valves

Joseph Thomas. Indian J Urol. 2010 Oct.

Abstract

Posterior urethral valves are the commonest cause of urethral obstruction in a male child. It has significant effects on the development of upper urinary tracts and in the evolution of urinary bladder function. The effect on the kidneys and the urinary bladder persists even after the successful management of the obstructing valves. A detailed evaluation of the associated bladder dysfunction will help in planning management protocols that will improve the long-term outcome of these patients.

Keywords: Bladder dysfunction; posterior urethral valve; valve bladder.

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Conflict of interest statement

Conflict of Interest: None declared.

References

    1. Hodges SJ, Patel B, McLorie G, Atala A. Posterior urethral valves. Sci World J. 2009;14:1119–26. - PMC - PubMed
    1. Levin RM, Monson FC, Haugaard N, Buttyan R, Hudson A, Roelofs M, et al. Genetic and cellular characteristics of bladder outlet obstruction. Urol Clin North Am. 1995;22:263–83. - PubMed
    1. Keating MA. The noncompliant bladder: Principles in pathogenesis and Pathophysiology. Prog Urol. 1994;8:348.
    1. Aitken KJ, Bägli DJ. The bladder extracellular matrix: Part I: architecture, development and disease. Nat Rev Urol. 2009;6:596–611. - PubMed
    1. Hutcheson JC, Stein R, Chacko S, Carr M, Canning DA, Zderic SA. Murine in vitro whole bladder model: A method for assessing phenotypic response to pharmacologic stimuli and hypoxia. Neurourol Urodyn. 2004;23:349–54. - PubMed